Hyperbaric Oxygen Chamber

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Hyperbaric oxygen therapy increases dissolved oxygen in the blood

Oxygen is found in two forms in the blood: hemoglobin-bound oxygen and dissolved oxygen in plasma. The amount of oxygen dissolved in the plasma is much smaller than the amount of bound oxygen, and the amount of dissolved oxygen is proportional to the pressure. There are parts of the body where the capillaries are narrow, blood cells cannot pass through, and combined oxygen cannot be reached, so they can only rely on dissolved oxygen. The oxygen generator does not change much to the dissolved oxygen in the blood, which is also the reason why the general oxygen absorption effect in the plateau area is average. Increasing the dissolved oxygen in the blood by increasing pressure is a more feasible way. The hyperbaric oxygen chamber can maintain the partial pressure of oxygen within a safe and effective range by flexibly adjusting the oxygen concentration or pressure of the ventilation, and gently and effectively improve the oxygen delivery to tissues and organs by increasing dissolved oxygen.

Hyperbaric oxygen therapy reduces free radicals and optimizes mitochondrial metabolism

Oxidative stress occurs when the production of reactive oxygen species exceeds the antioxidant capacity. The reduction in mitochondrial efficiency plays an important role in aging-induced oxidative stress, as mitochondria are the primary site for the production of ROS within cells. Hyperbaric oxygen therapy increases oxidase activity in mitochondria and increases oxidative metabolism in cells and tissues, particularly pathways in the mitochondrial TCA cycle.

At the same time, it causes an increase in the adaptability of superoxide dismutase (SOD), which helps the body to fight free radicals and antioxidants; On the other hand, it may prevent the formation of xanthine oxidase and reduce the production of superoxide radicals and hydrogen peroxide.

Hyperbaric oxygen therapy delayed Hormesis enhances antioxidant capacity

Reactive oxygen species are typical "stimulant molecules", i.e., low concentrations benefit the body, and high concentrations damage the body. The oxygen content of the cell environment is positively correlated with the amount of intracellular free radical production, and when hyperbaric oxygen chamber treatment slightly increases the oxygen supply to the cell, the concentration of intracellular reactive oxygen species increases slightly, which stimulates the cell viability.

A small amount of reactive oxygen species can awaken the expression of anti-stress and antioxidant genes in the body, improve the ability of cells to scavenge free radicals, and improve cell survival (shown in the red box on the left). At the end of chamber therapy, reactive oxygen species return to normal, but the previously induced antioxidants have a longer half-life and continue to exert protection. Consistent use of the chamber can maintain high levels of antioxidants and repair various oxidative damage more quickly – similar to the thrilling effects of exercise.

Hyperbaric oxygen therapy inhibits hypoxia-inducible factor

During hypoxia, the structure of hypoxia-inducible factors is maintained, and they can enter the nucleus and attach to the non-coding region of the gene (the DNA sequence that regulates the on/off of the gene), causing signal transduction related to cell survival, thus changing the metabolic pattern of the cell. When oxygen is sufficient, hypoxia-inducible factors undergo hydroxylation reactions, and then are transported to the proteasome for degradation and elimination.

Hyperbaric oxygen inhibits HIF signaling, improves cell metabolism, and improves human health by periodically replenishing oxygen in tissues and organs.

Aging: Israel scientists use hyperbaric oxygen therapy to reverse human aging

In 2020, Israel scientists published a clinical trial in Aging, which showed that after continuous hyperbaric oxygen therapy to a group of elderly people, in just three months, the cellular aging process could be significantly stopped or even reversed. The clinical program recruited 35 elderly people aged 64 years and older to receive hyperbaric oxygen therapy once a day, 5 times a week, for 60 consecutive sessions.

After hyperbaric oxygen therapy, two key indicators of aging are reversed. Telomere length: Telomere length of peripheral blood mononuclear cells increased by more than 20% after hyperbaric oxygen therapy, and the change of B cells was the most significant. Senescent cells: 10-37% reduction in senescent cells in peripheral blood mononuclear cells after hyperbaric oxygen therapy.

Science: Hyperbaric oxygen therapy activates VEGF signaling, prolongs life by 50%

On July 30, 2021, the top international journal "Science" published a blockbuster study, revealing that by enhancing the VEGF signaling pathway, it can increase healthy survival and extend the lifespan of mice by up to 50%.

Hyperbaric oxygen therapy application

Microhyperbaric oxygen therapy belongs to the category of health care, which is a relatively safe measure, less stressful and safer. It is suitable for the elderly, patients with chronic diseases, beauty lovers, sub-healthy people, athletes, obese people, postoperative rehabilitators, etc. Hyperbaric oxygen chamber equipment is commonly found in nursing homes, rehabilitation centers, home physiotherapy, medical beauty institutions, gyms, high-end hotels, confinement centers, community elderly care, gymnasiums, high-end clubs, plateau areas and other diversified scenarios.

Daily oxygen care

· Quickly increase the content of bound oxygen and dissolved oxygen, accelerate blood flow, repair cells, and help balance metabolism and body;

· May help relieve cardiocerebral symptoms.

Functional stagnation

· Common sub-health conditions: insufficient exercise, poor metabolism, cardiocerebral exhaustion, slow blood flow, cerebral hypoxia, etc.;

· When blood flow itself is blocked, hyperbaric oxygen therapy can be used to rapidly increase blood oxygen content, improve the body's utilization rate of oxygen, and optimize body functions

Damaged skin

· Helps improve skin metabolism, accelerate metabolite clearance and cell regeneration;

· Improves skin elasticity and radiance, and may protect the skin from UV damage;

· It assists in post-aesthetic recovery, reduces inflammation and edema, accelerates tissue regeneration, and helps surgical site repair

Post-operative recovery

· Helps inhibit the growth and reproduction of anaerobic bacteria in the human body and reduce the production of mycin;

· It has a positive synergistic effect with some antibiotics to improve the body's antibacterial and antibacterial ability;

· Sufficient oxygen can meet the energy requirements of the metabolism of the tissues around the incision .